The development and deployment of games with a purpose beyond entertainment and with considerable connotations with more serious aims is an exciting area with immense academic but also commercial potential. This potential presents both immediate opportunities but also numerous significant challenges to the interested parties involved, as a result of the relatively recent emergence and popularity of the medium. The VS Games 2013 conference aims to address this variety of relevant contemporary challenges that the increasingly cross-disciplinary communities involved in serious games are currently facing. This will be achieved by, amongst other ways, the comprehensive dissemination of successful case studies and development practices, the sharing of theories, conceptual frameworks and methodologies and, finally, the discussion of evaluation approaches and their resulting studies.